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Hereditary Central Nervous System Demyelinating Diseases - 20 Studies Found

Status Study
Completed Study Name: Imaging Study of the White Matter Lesions in Children With Metachromatic Leucodystrophy
Condition: Late Infantile Metachromatic Leukodystrophy
Date: 2011-03-09
Interventions: Other: High-field MRI (3 Teslas)

Completed Study Name: Efficacy METAZYM for the Treatment Metachromatic Leukodystrophy Treated With Hematopoietic Stem Cell Transplantation
Condition: Metachromatic Leukodystrophy
Date: 2011-02-23
Interventions: Drug: rhARSA intravenous infusion 100U/kg every other week for 18 months
Withdrawn Study Name: An Observational Study of Pediatric Subjects With Globoid Cell Leukodystrophy (GLD)
Condition: Leukodystrophy, Globoid Cell
Date: 2010-03-24
Completed Study Name: Study of Human Central Nervous System (CNS) Stem Cells Transplantation in Pelizaeus-Merzbacher Disease (PMD) Subjects
Condition: Pelizaeus-Merzbacher Disease
Date: 2009-10-28
Interventions: Biological: HuCNS-SC cells intracerebral transplantation
Completed Study Name: The Natural History of Infantile Globoid Cell Leukodystrophy
Condition: Infantile Globoid Cell Leukodystrophy
Date: 2009-09-23
Active, not recruiting Study Name: Diffusion Tensor Imaging (DTI) in Infants With Krabbe Disease
Condition: Krabbe Disease
Date: 2008-11-07
Completed Study Name: Effect of Warfarin in the Treatment of Metachromatic Leukodystrophy
Condition: Metachromatic Leukodystrophy
Date: 2008-05-21
Interventions: Drug: Warfarin Oral administration (QD), variable dosage: patients will undergo blood test for PT/INR at
Terminated Study Name: Open-Label Extension Study of Recombinant Human Arylsulfatase A (HGT-1111) in Late Infantile MLD
Condition: Late Infantile Metachromatic Leukodystrophy
Date: 2008-05-19
Interventions: Drug: HGT-1111 Patients currently dosed with 100 U/kg or 200 U/kg will continue this treatment. Patients
Active, not recruiting Study Name: The Natural History of Metachromatic Leukodystrophy
Condition: Metachromatic Leukodystrophy
Date: 2008-03-11
Completed Study Name: Long-term Metazym Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)
Condition: Late Infantile Metachromatic Leukodystrophy
Date: 2008-02-29
Interventions: Biological: Recombinant human Arylsulfatase A (rhASA) intravenous infusion, every other week for 26 week
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