Search for Clinical Trial Results
Leber Congenital Amaurosis - 16 Studies Found
| Status | Study |
| Completed |
Study Name: Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations Condition:
Date: 2009-11-12 Interventions: Drug: QLT091001 oral QLT091001 administered once daily for 7 days |
| Completed |
Study Name: Clinical Gene Therapy Protocol for the Treatment of Retinal Dystrophy Caused by Defects in RPE65 Condition: Leber Congenital Amaurosis Date: 2011-11-24 Interventions: Drug: rAAV2/4.hRPE65 One injection in on eye |
| Completed |
Study Name: Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT Condition:
Date: 2015-10-09 Interventions: Other: No treatment: retrospective chart review |
| Active, not recruiting |
Study Name: Phase I Trial of Gene Vector to Patients With Retinal Disease Due to RPE65 Mutations Condition:
Date: 2007-05-31 Interventions: Genetic: rAAV2-CBSB-hRPE65 One or two, uniocular, subretinal injections; relative doses: 0.3X (Cohort 1) |
| NOT_YET_RECRUITING |
Study Name: A Safety and Efficacy Study of HG004 in Subjects With Leber Congenital Amaurosis Condition: Date: 2026-01-10 Interventions: Low dose Medium dose High dose |
| Completed |
Study Name: Safety and Efficacy Trial of HG004 for Leber Congenital Amaurosis Related to Rpe65 Gene Mutations (STAR) Condition: Leber Congenital Amaurosis Date: 2026-01-10 Interventions: Low dose Medium dose High dose |