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Leber Hereditary Optic Neuropathy - 21 Studies Found

Status Study
Completed Study Name: Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy
Condition: Leber Hereditary Optic Neuropathy
Date: 2014-06-25
Interventions: Drug: cyclosporine
Withdrawn Study Name: Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)
Condition: Leber's Hereditary Optic Neuropathy
Date: 2011-12-16
Interventions:
  • Drug: Idebenone
  • Drug: Placebo
Completed Study Name: Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey
Condition: Leber Hereditary Optic Neuropathy (LHON)
Date: 2013-06-26
Recruiting Study Name: Post Authorisation Safety Study With Raxone in LHON Patients
Condition: Leber's Hereditary Optic Neuropathy (LHON)
Date: 2016-04-25
Interventions: Drug: Idebenone Raxone 900mg/day as per Raxone SmPC and medical judgement of treating physician.
Recruiting Study Name: Study to Assess the Efficacy and Safety of Raxone in LHON Patients
Condition: Leber's Hereditary Optic Neuropathy (LHON)
Date: 2016-05-12
Interventions: Drug: Idebenone Other Name: Raxone
Completed Study Name: A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)
Condition: Optic Atrophy, Hereditary, Leber
Date: 2007-09-11
Interventions: Drug: curcumin curcumin 250 mg twice a day in the first group. placebo 1 capsule twice a day in the seco
Completed Study Name: Biomechanics of Optic Neuropathy
Condition: Optic Neuropathy
Date: 2016-08-28
Interventions: Device: magnetic resonance image (MRI)
Active, not recruiting Study Name: Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation
Condition: Optic, Atrophy, Hereditary, Leber
Date: 2016-01-07
Interventions:
  • Genetic: GS010

Completed Study Name: Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation
Condition: Optic, Atrophy, Hereditary, Leber
Date: 2016-01-07
Interventions:
  • Genetic: GS010

Completed Study Name: Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND1 Mutations
Condition: Leber Hereditary Optic Neuropathy (LHON)
Date: 2025-11-04
Interventions: The starting dose is 1.5�108 vg, 0.05 mL eye/dose.If drug-related dose-limiting toxicity (DLT) events are observed in < 2 of the 6 evalu
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