Roussy-Lévy Syndrome, also known as hereditary areflexic dystasia, is a rare genetic neuromuscular disorder that typically becomes apparent during early childhood.
The disorder is characterized by incoordination, poor judgment of movements, and absence of reflexes of the lower legs and, eventually, the hands; weakness and degeneration (atrophy) of muscles of the lower legs; abnormally high arches of the feet with an increased extension of the toes and tremors of the hands.
1. Roussy-Levy Syndrome is inherited as an autosomal dominant genetic trait.
2. Roussy-Lévy is inherited through autosomal dominant genetic transmission. Human traits, including classic genetic diseases, are the product of the interaction of two genes, one received from the father and one from the mother.
3. In dominant disorders, a single copy of the disease gene (received from either the mother or father) will be expressed, “dominating” the other normal gene and resulting in the appearance of the disease.
4. The risk of transmitting the disorder from affected parent to offspring is 50 percent for each pregnancy, regardless of the sex of the resulting child.
5. Scientific evidence published in 1998 indicated that Roussy Lévy Syndrome appears to be a form of Charcot Marie Tooth Disease because it is caused by partial duplication of the same gene that causes CMT
6. Roussy-Lévy is a rare disorder that affects both sexes in equal numbers. Onset is during early childhood.
Increased extension of the toes and tremors of the hands
Weakness and degeneration (atrophy) of muscles of the lower legs,Abnormally high arches of the feet
Painkillers,Anti-inflammatory drugs,Corticosteroids,Physical therapy and rehabilitation