Spinal muscular atrophy type 3 is an inherited progressive neurodegenerative disease. SMA is caused by alterations (mutations) in the genes that make proteins needed to support motor neuron function. The degree of genetic involvement determines what type of SMA you have as well as the severity of symptoms.1
Since SMA is a genetic condition, there are no specific lifestyle factors known to cause or prevent it.
Certain lifestyle risk factors have been linked to several types of motor neuron disease, but researchers don't know if any are specifically linked to SMA.13
However, there are some lifestyle factors and habits that may make it more likely you could develop complications from the condition.
Lifestyle factors that can predispose someone with SMA to complications or other health problems include:
1. Sedentary lifestyle. If you have motor weakness, inactivity can contribute to health problems, such as upper respiratory infections, constipation, and bedsores (pressure ulcers). An exercise program that's customized to your abilities can help you maintain or improve muscle function.14
2. Exposure to infectious diseases: Chronic conditions like SMA can affect your immune system. Avoiding people who are sick with contagious infections helps you avoid potentially serious complications of infectious illnesses.15
3. Unhealthy diet: A diet that's lacking in nutrition makes it harder for the body to fight infections. If the body doesn't get adequate energy from food, it may make muscle weakness from SMA feel worse.
4. Optimizing your overall health with lifestyle strategies cannot alter SMA, but it can help you minimize the risk of complications and improve your quality of life.
Floppy or weak arms and legs,Movement problems – such as difficulty sitting up, crawling or walking.
twitching or shaking muscles
Bone and joint problems – such as an unusually curved spine (scoliosis),Swallowing problems,Breathing difficulties
Nusinersen (Spinraza),Onasemnogene abeparvovec-xioi (Zolgensma),Risdiplam (Evrysdi)