About xanthoma tuberosum

What is xanthoma tuberosum?

Hyperlipoproteinemia type III, also known as dysbetalipoproteinemia or broad beta disease, is a rare genetic disorder characterized by improper breakdown (metabolism) of certain fatty materials known as lipids, specifically cholesterol and triglycerides. This results in the abnormal accumulation of lipids in the body (hyperlipidemia). Affected individuals may develop multiple yellowish, lipid-filled bumps (papules) or plaques on the skin (xanthomas). Affected individuals may also develop the buildup of fatty materials in the blood vessels (artherosclerosis) potentially obstructing blood flow and resulting in coronary heart disease or peripheral vascular disease. Most cases of hyperlipoproteinemia type III are inherited as an autosomal recessive trait.

What are the symptoms for xanthoma tuberosum?

A skin condition called xanthoma tuberosum is where specific fats begin to build under the surface of the skin. A branched-out type of Xanthoma is Xanthoma Tuberosum. Here, Xanthoma accumulates in the areas close-by joints. It is affiliated with lipid disorders, liver cirrhosis, and some thyroid disorders.

Symptoms of Xanthoma Tuberosum are as follows:

1. Firm, elevated wax-like in appearance

2. Papilla or bumps

3. Skin-colored, pink, yellowish

4. Increased blood lipids

5. Painless

6. High or low level of blood triglyceride (a type of fat)

7. Uncontrolled cholesterol levels

8. Growth of fats presenting themselves in a clump underneath the skin. These can appear anywhere on the span of the body—joints, knees, elbows, feet, hands, buttocks.

Symptoms
Fatty growths develop underneath the skin. These growths can appear anywhere on the body, especially in the joints (knees and elbows, feet, hands and buttocks)
Conditions
Fatty growths develop underneath the skin
Drugs
Surgical removal,Laser surgery,Chemical treatment with trichloroacetic acid

What are the causes for xanthoma tuberosum?

Xanthoma Tuberosum is nothing but a colonized group of lipid-laden histiocytes. Common in Hyperlipidemia patients. Largely seen in skin and subcutis, rare in deep, soft tissues of the hand and feet. Well-bound, frequent multiple slow-paced growth of masses.

Causes of Xanthoma Tuberosum are enlisted below:

1. Particular kinds of cancer

2. Diabetes (Diabetes Mellitus)

3. The subtype of diabetes, where the body fails to control the amount of glucose in the blood while the kidneys produce excess urine.

4. A rise in Blood Cholesterol levels

5. Genetic Metabolic Disorders (Example: Familial Hypercholesterolemia)

6. Visible Inflammation and Swelling of the Pancreas

7. Scarred liver because of the blocked bile duct (Example: Primary Biliary Cirrhosis)

8. Below Average Active Thyroid (Example: Hyperthyroidism)

9. Cholestatic Liver Disease

10. Medications (Example: Estrogen and Protease Inhibitors)

11. Spiked Levels of Fats

12. Diseases Vulnerable to Cause High Blood Sugar Levels

13. Nephritic Syndrome, a disorder detrimental to the blood vessels passing through the kidneys.

Symptoms
Fatty growths develop underneath the skin. These growths can appear anywhere on the body, especially in the joints (knees and elbows, feet, hands and buttocks)
Conditions
Fatty growths develop underneath the skin
Drugs
Surgical removal,Laser surgery,Chemical treatment with trichloroacetic acid

What are the treatments for xanthoma tuberosum?

As Xanthomas are deposits of lipids underneath the skin or maybe in the subcutaneous tissue, they come under Dyslipidemia-related conditions. TX (Tuberosum Xanthoma) is a type of lipid metabolism imbalance, including but not limited to the knees and elbows.

Diagnosis:

The doctor extracts a sample of tissue from the growth and sends it off to the laboratory for a medical examination.

Treatments For Xanthoma Tuberosum Are Given Below:

1. Laser Dioxide Treatment: CO2 Laser permits treatment of a broad range of TX in only one session under local anesthesia. It is considered to be a rather effective alternative for surgery for widespread lesions. However, this results in the recurrence of symptoms.

2. Simplistic Excision of the Mass in case of Compromised Function: Chemical Treatment with Trichloroacetic Acid. It helps fall off dead skin cells and stimulates the growth of newer cells. It's usually a treatment used for genital as well as anal warts, a consequence of papillomavirus (HPV). An intense chemical that wipes out warts through the destruction of proteins in the cells.

Symptoms
Fatty growths develop underneath the skin. These growths can appear anywhere on the body, especially in the joints (knees and elbows, feet, hands and buttocks)
Conditions
Fatty growths develop underneath the skin
Drugs
Surgical removal,Laser surgery,Chemical treatment with trichloroacetic acid

What are the risk factors for xanthoma tuberosum?

Xanthomas can differ in terms of size. The growth may range from the size of a pinhead to that of a grape, yellow or orange-colored flat bumps under the skin. While these don't result in any pain, they could be sensitive and cause itchiness. Such clusters of growth can be seen on a common area of the skin or in numerous individual growths on the body.

Risk Factors for xanthoma tuberosum entail all of the Medical Conditions Enlisted Below:
1. Hyperlipidemia or otherwise known as levels of high blood cholesterol
Diabetes
2. Hypothyroidism, a condition where the thyroid fails to continue the production of hormones
3. Primary Boluses Cirrhosis, the slow destruction of bile ducts in the liver
4. Cholestasis, a condition where the supply of bile from the liver slows down or ultimately stops.
5. Nephrotic Syndrome, a disorder in which the blood vessels in the kidneys are damaged.
6. Hematologic disease, a genetic condition affecting the ability of the body to break substances in order to sustain crucial bodily functions, like digestion of fats.
7. Cancer, a severe condition where the growth of malignant cells is rapid and uncontrolled.
8. Side effects of particular medications, like Tamoxifen, Prednisone, Cyclosporine
9. High Triglyceride Levels

Symptoms
Fatty growths develop underneath the skin. These growths can appear anywhere on the body, especially in the joints (knees and elbows, feet, hands and buttocks)
Conditions
Fatty growths develop underneath the skin
Drugs
Surgical removal,Laser surgery,Chemical treatment with trichloroacetic acid

Video related to xanthoma tuberosum